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It co-localizes with multiple hormones and neurotransmitters, suggesting broad regulatory functions

Intramuscular B12 injections can also be used

The free peptide is usually represented with an unmodified amino terminus and a C-terminal carboxylic acid

note that daily dosing is only for the activation phase of the GLOW protocol (weeks 1-4) , decreasing to 5x per week for the remodeling phase (weeks 5-8), and further reduced to 2-3x per week during maintenance (weeks 9-12)

Preferred for patients with MTHFR mutations (which are common in the general population) and for patients who want the most directly usable form