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In addition, a large number of infiltrating inflammatory cells infiltrate and secrete abundant oxygen-free radicals and pro-inflammatory cytokines, which further induce renal damage and accelerate renal fibrogenesis and kidney injury (53)

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H1 blockers include cetirizine (Zyrtec), loratadine (Claritin), levocetirizine (Xyzal), fexofenadine (Allegra) or chlorphenamine (Chrorphen)

Doxorubicin-induced cardiotoxicity and the emerging role of SGLT2 inhibitors: from glycemic control to cardio-oncology

Protein concentration was measured by Bradford protein assay