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Exendin-4, a GLP-1R agonist, also suppressed basal expression of several inflammatory mediators and in combination with phosphodiesterase inhibitors, decreased CXCL10 expression by IFN- (a type II-interferon) in human islets and in MIN6 cells (a mouse -cell line)

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It also blocks glucagon, a hormone that raises blood sugar, slows digestion to reduce sugar release into the bloodstream, and increases feelings of fullness after eating

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The dose that got you to your goal weight and the dose you need to maintain it may be different, and finding that maintenance dose is a clinical conversation rather than an assumption