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Liraglutide restored proper autophagic flux by alleviating the accumulation of P62 (an autophagy dysfunction marker) in the lacrimal gland, reduced oxidative damage by enhancing clearance of ROS and promoting cellular repair mechanisms, and potentially addressed dry eye syndrome (Sun et al., 2025)
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Leptin levels also drop significantly as fat mass decreases, signaling to your brain that energy reserves are depleted and conservation is necessary
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