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Mitochondrial function interference or mitochondrial damage is also one of the mechanisms of pathogenesis of PD (71)

While pharmacotherapies combined with behavioral interventions can be effective, relapse rates remain high, exceeding 50% within the first-year post treatment (46)

Patients should consult their GP or pharmacist before starting any laxative, particularly if they have underlying gastrointestinal conditions or are taking other medications

Those with higher blood pressure levels before starting treatment may also see larger reductions than individuals whose blood pressure is already within a healthy range.

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