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The small molecule library used for screening can be obtained from active components of natural products, endogenous bioactive substances, existing drugs, or through tissue chemistry and high-throughput screening
This ensures that our patients receive the highest standard of care during their treatment
In rodent studies, NNMT inhibition was associated with shifts in metabolic substrate utilisation
The difference in IC50 values between the combination and all-trans-RA alone was almost three times more efficient, which means that the cytotoxicity of the combination is higher
Addiction 104, 587592
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