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134 have generated an anti-idiotypic antibody (CG-86) which mimics an epitope on porcine GH and investigated the inhibitory effects on GH signaling and cell proliferation, which demonstrated the potential utility of this approach for generating GH antagonists
Furthermore, Vitamin C is sensitive to its environment
In this study, a significant decrease in cell viability after XPF knockdown, which also reduces ERCC1 levels, was observed in the most resistant tumor cell line, confirming that DNA repair has a fundamental role in cisplatin resistance and variation in the protein levels of XPF and ERCC1 can explain, at least partially, the acquired resistance in tumors when compared to a normal fibroblast
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