Common research applications include single-receptor pharmacology (semaglutide and liraglutide as GLP-1 reference agonists), dual-receptor comparison studies (tirzepatide for GIP/GLP-1, mazdutide and survodutide for GLP-1/glucagon), triple-receptor research (retatrutide), and multi-pathway combinations using amylin agonists alongside incretin agonists (cagri-sema, retatrutide+cagrilintide)
Peirson Center for Children
However, semaglutide can indirectly increase UTI risk through dehydration from GI side effects like nausea, vomiting, and diarrhea
In this letter, we summarise the findings of the most recent studies that have reported the potential impact of GLP-1RAs on the residual gastric content (RGC), in light of an increased risk of aspiration pneumonia for patients undergoing general anaesthesia and/or deep sedation (Table 1)
What is their role in emerging diseases