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Since the more mildly-affected participants often responded well to cofactor therapy alone, and that the side effects of the cofactors are generally much less than that of the medications [5 and author's experience], a trial of cofactor and dietary therapy alone may be warranted in most CVS patients encountered in clinical practice, with amitripyline or cyproheptidine added in refractory cases
In addition, while the company sells compounded GLP-1 drops primarily for weight loss, there is only one comparative FDA-approved GLP-1 drug that is taken orally, a pill that is only approved to treat diabetes
Besides this, the presence of free metals (Fe, Cu, Mn) derived from the metallo-protein complex phenomenon also contributes to ROS production