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None of GHK-Cu, BPC-157, or TB-500 has an approved human indication, and the GLOW combination specifically has no clinical trial establishing safety or efficacy in humans

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For patients on established B12 injection therapy, monitoring is based primarily on clinical response and haematological parameters rather than routine serum B12 measurements, which may remain very high without indicating harm or overtreatment

Individuals with certain health conditions, such as Lebers disease (a hereditary eye disease), should avoid B12 injections, as they can exacerbate symptoms

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