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Mutations in BRCA1 or BRCA2 increase the risk of breast and ovarian cancer by 5- and 1030-fold, respectively [34,35,36]

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Research has shown increased phosphorylation of extracellular signal-regulated kinases (ERK) 1 and 2, along with their downstream targets, including c-Fos, c-Jun, and Egr-1, which are molecules involved in cell growth, migration, and angiogenesis