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Abstract Chemotherapy-induced peripheral neuropathy (CIPN) is one of the most challenging dose-limiting toxicities in contemporary oncology, affecting 1985% of patients receiving neurotoxic chemotherapy agents

Yes and the combination is often more effective than either alone

& Pearce, D

As mentioned, some clinics have already started applying this NNMT inhibitor to humans, even though the FDA has made no ruling on its safety, making human trials paramount