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Ele desempenha um papel crucial na regulao da homeostase glicmica, estimulando a secreo de insulina pelas clulas beta pancreticas de maneira dependente da glicose e inibindo a liberao de glucagon pelas clulas alfa
Cardiovasc Hematol Agents Med Chem 16(1):3543 Boland ML, Laker RC, Mather K, Nawrocki A, Oldham S, Boland BB, Lewis H, Conway J, Naylor J, Guionaud S, Feigh M, Veidal SS, Lantier L, McGuinness OP, Grimsby J, Rondinone CM, Jermutus L, Larsen MR, Trevaskis JL, Rhodes CJ (2020) Resolution of NASH and hepatic fibrosis by the GLP-1R/GcgR dual-agonist Cotadutide via modulating mitochondrial function and lipogenesis
M., Lloyd, B
The trial randomized 241 patients with chronic HF with reduced left ventricular ejection fraction to receive liraglutide or placebo
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