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Together, these results demonstrate that reprogramming BoNT/X protease to cleave gasdermin D is achievable through iterative substrate design, negative selection and circuit optimization

When toxic exposure or chronic inflammation is too high, Phase 1 rapidly uses up the liver's glutathione reserves, causing Phase 2 to come to a screeching halt

Glutathione IV therapy refers to the administration of glutathione directly into the bloodstream through an intravenous (IV) infusion (usually a slow drip via a vein)

Eligible patients may use GLOW Blend injections at home after provider instruction