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So, if your research protocol calls for a dose of 500mcg, you would draw the solution to the 10-unit mark on the syringe (50mcg/unit * 10 units = 500mcg)
A two-stage procedure was pre-specified: in Stage 1 exposure was considered equivalent between the severe RI group and the normal renal function group if the 95% confidence intervals (CIs) for the ratio of AUC (unadjusted) were contained within the pre-specified no effect interval of 0.701.43 (both inclusive)
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Once-Weekly Semaglutide in Adults with Overweight or Obesity. New England Journal of Medicine, 2021
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