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doi: 10.1016/j.ejmech.2024.116387 87
The glucose-lowering efficacy of long-acting GLP-1 RAs is strongly associated with residual pancreatic -cell function and mass, a relationship extensively reported by multiple research groups [40,41,42,43]
Further large-scale trials are warranted to confirm these findings
Ultimately, the accumulation of lipid peroxidation byproducts severely compromises membrane integrity, causing irreversible cell death (19)
DOI : 10.1038/s41366-026-02061-y.
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