glp-1 logo The Oral Era Is Here: What It Means for Life Sciences Careers Are GLP-1s Longevity Drugs? |

Well-controlled hypertension is not an absolute contraindication, but PT-141 can transiently elevate blood pressure

Study #2: Menstrual cycle regularity The same meta-analysis found significant improvement in menstrual regularity (SMD: 1.72, P 15 pounds during washout: This suggests intervention needed: Reassess calorie intake (are you eating significantly more than maintenance?) Increase protein target to 120-150g daily Add resistance training if not already doing it Consider extended washout (4 months instead of 3) to stabilize weight Meet with dietitian for structured meal plan Important consideration: Significant weight regain may impact the fertility improvements you gained from GLP-1 use

The authors concluded that caution was necessary when treating patients with incretins

Huang et al., 2024b

doi.org/10.1001/jama.2023.19574