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Now, millions are racing to get prescriptions, and experts have begun to calculate the global impact of a possibly widespread reduction in rates of obesity

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Tang H, Donahoo WT, DeKosky ST, Lee YA, Kotecha P, Svensson M, Bian J, Guo J (2025) GLP-1RA and SGLT2i Medications for Type 2 Diabetes and Alzheimer Disease and Related Dementias

Potential links between suicide or mental health conditions and GLP-1 receptor agonists particularly semaglutide have been the focus of several recent analyses and an FDA investigation, which have shown mixed results