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Its the most common variant in fact, more Americans have at least one copy of it than those who dont
Homologous binding sites in yeast isocitrate dehydrogenase for cofactor (NAD+) and [PMID: 12562755] Laboratory literature summary: Homologous binding sites in yeast isocitrate dehydrogenase for cofactor (NAD+) and allosteric activator (AMP)
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In the context of cancer therapy, our results suggest that stimulation of nucleotide synthesis in combination with GSH depletion may be especially toxic
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