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In Australia, these drugs are popular for managing obesity and diabetes, but knowing the contraindications helps ensure they're used appropriately
Comparison between different measures of body fat with kidney function decline and incident CKD
Bowsman et al
Current Diabetes Reviews, 16
Overall, the affinitypotency profile of tirzepatide was 360-fold weaker relative to mGIP at the mGIPR, with similar or slightly reduced potency compared to GLP-1 at the mGLP-1R (Extended Data Table 1)
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