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In fact, some athletes take supplements of vitamin B12 before big games or competitions
Long-term continuous use without breaks may lead to reduced effectiveness
[16] [121] Upon leaving the stomach the hydrochloric acid of the chyme is neutralized in the duodenum by bicarbonate, [122] and pancreatic proteases release the vitamin from HC, making it available to be bound by IF, which is a protein secreted by gastric parietal cells in response to the presence of food in the stomach
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B12 (cobalamin) is water-soluble
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