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This has become known as the bacterial contamination hypothesis 39

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M2-like TAMs, which dominate many solid tumors, create a ferroptosis-resistant niche by exporting iron through ferroportin, supplying cysteine precursors that support glutathione synthesis, and releasing IL-10, TGF-, and lipid mediators that dampen oxidative stress

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[6] Pyruvate is often used in the Krebs cycle , which is a collection of reactions that generate energy through the creation of ATP