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Biochim Biophys Acta 460:299307 Leary SC, Hill BC, Lyons CN, Carlson CG, Michaud D, Kraft CS, Ko K, Glerum DM, Moyes CD (2002) Chronic treatment with azide in situ leads to an irreversible loss of cytochrome c oxidase activity via holoenzyme dissociation

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[1] [2] However, a small proportion is converted via the cytochrome P450 enzyme system into a toxic metabolite called N-acetyl-p-benzoquinone imine (NAPQI)

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