Nausea (most common, especially during first 1 to 2 weeks of a new dose) Diarrhea or, just as often, constipation Vomiting (less common but more likely at 9 to 12 mg) Reduced appetite, food noise quieting down (this is the goal, not a side effect) Skin sensitivity (dysesthesia): tingling, prickly feeling, or sunburn-like skin
It inhibits NNMT (nicotinamide N-methyltransferase), an enzyme regulating metabolism, fat storage, and NAD+ consumption.[4][27][6] NNMT methylates nicotinamide, a NAD+ breakdown product, diverting it from recycling and reducing available NAD+
AHK-Cu is a copper-binding tripeptide studied for its role in cell signaling, extracellular matrix regulation, and tissue-repair pathways
The compound has many similarities to the peptide hormone -melanocyte-stimulating hormone
an unusual or allergic reaction to methylcobalamin, cobalt, other medicines, foods, dyes, or preservatives