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Following the CHMP's formal opinion, the final decision will be submitted to the European Commission for a legally binding resolution applicable across all EU Member States.

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The constipation burden appears lower with retatrutide

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R.MomenanR.et al (2001)

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Tocotrienols have demonstrated inhibitory effects on the phosphorylation of the PI3k/Akt signaling pathway, resulting in the downregulation of key signaling molecules including endothelial nitric oxide synthase (eNOS), glycogen synthase kinase 3 (GSK3), and extracellular signal-regulated kinase (ERK)

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Four studies were excluded following the full-text article assessment

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