Chen Z, Hu T, Zhu S, Mukaisho K, El-Rifai W, Peng DF
We have recently shown that the collateral sensitivity of resistant cells to these drugs is dependent on P-gp expression and activity, whereby stimulation of its ATPase activity triggers a rise in reactive oxygen species (ROS) leading to heightened oxidative cell death of resistance cells [14,15,16,17]
Presented for research literature review only Schibler U (2020)
The roles of Src and ERK in regulating microtubule nucleation were further supported by inhibitor studies and molecular genetic approaches
Consequently, improving amylin-based medicines focuses on enabling longer action, resulting in weekly use, possibly even oral use and, most importantly, combining the functions of more than one hormone known for being involved in glucose control and the promotion of satiety