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Such hyper-inflammatory conditions could trigger NO release and inhibit EPO synthesis causing anemia of inflammation (AI) 476
Glutathione S-transferases (GST) are a family of homodimeric enzymes that play a pivotal role in cell detoxification by catalyzing the conjugation of many endogenous and exogenous hydrophobic electrophiles (such as xenobiotics) with reduced glutathione, thus neutralizing their effects within the cellular environment [10]
1 , 2 The BBB is an active and dynamic organ that ensures adequate concentration of essential compounds such as oxygen and glucose and at the same time protects the brain from deleterious substances in the peripheral circulation
Theyre evaluated through different study designs because they act on different pathways
One case-control study reported that selenium-responsive glutathione peroxidase 1 (GPx1) activity was significantly lower in Keshan patients compared to healthy individuals
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