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Based on prior data implicating macrophage FXa as a PAR2 activator in obesity (40), we next addressed the role of myeloid cellderived FXa for the regulation of GIP
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In fact, a B12 deficiency can sometimes lead to weight loss due to reduced appetite
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A prespecified analysis of SELECT further suggested reductions in composite HF outcomes among participants with and without prior HF, although these findings were secondary analyses rather than HF-dedicated trial endpoints [17]
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