It is based on the native GIP sequence with modifications that enable cross-reactivity at the GLP-1 receptor, plus a C20 fatty diacid chain attached via a linker for albumin binding (half-life approximately 5 days)
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The most common electrolyte shifts with GLP-1 RA use, when they occur, are losses of chloride and potassium from vomiting, sometimes accompanied by changes in sodium levels, Dr
Moderator: -Claire OReilly, Senior Lecturer School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Australia Panellists: -Sarira El-Den, Lecturer School of Pharmacy, Faculty of Medicine and Health, The University of Sydney, Australia -Karlee Johnston, Associate Lecturer Pharmacology Australian National University, Australia -Aiwen Wang, Principal Clinical Pharmacist, Lecturer Singapore General Hospital (SGH), Singapore