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the authors reported a significant reduction in all-cause mortality (p=0.009) in the group of transplant recipients receiving steroids, treated with GLP-1 RAs, indicating a 38% lower risk of death compared to nonusers (55)

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Freund P, Wheeler-Kingshott CA, Nagy Z, Gorgoraptis N, Weiskopf N, Friston K, et al

Given that serotonin synthesis pathways are similar between the brain and periphery and across mammalian species, we here examine in humans the following hypotheses in both CFS and hypothyroidism with fatigue: (1) serum serotonin (S-5-HT) levels are low, (2) L-carnitine supplementation is associated with increased S-5-HT levels and reduced fatigue, and (3) there exists a correlation between peripheral S-5-HT and fatigue levels

Ozempic (semaglutide) is a GLP-1 receptor agonist licensed in the UK for type 2 diabetes management, administered as a once-weekly subcutaneous injection