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Consistent with these beneficial effects being mediated through adipose tissue, lipodystrophic mice with severely depleted adiposity, or mice with adipose-specific deletion of FGFR1 have blunted glycemic responses to FGF21 (240, 241)
601 ACSL4 expression is increased in dopaminergic neurons of the substantia nigra in both PD patients and animal models
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Reduces Oxidative Stress Glutathione directly neutralizes reactive oxygen species (ROS), helping to calm mast cell reactivity and lower inflammation
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