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The combination is synergistic
In adults, treatment length varies based on symptom relief and IGF-1 targets, and some may use it indefinitely if benefits persist (with periodic re-evaluation)
Mounjaro, Zepbound (tirzepatide) Mechanism: Mimics incretin hormones to regulate blood sugar, reduce appetite, slow gastric emptying While technically peptides, GLP-1 agonists represent a distinct category due to their metabolic mechanisms
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