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Research shows BPC-157 increases the stimulation of blood vessels through VEFG, upregulates early growth response genes, and increases nitric oxide through NOS3 stimulation.[ref] Here are a few of the studies in detail: A 2014 study outlined one mechanism of action, showing that BPC-157 enhances growth hormone receptors directly in the tendon, increasing growth hormone in the tendon

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Furthermore, both CLO doses counteracted these effects and downregulated -SMA

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