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These cardiovascular benefits likely require sustained, adequate receptor activation across all three targets, raising further questions about whether microdosing preserves them
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Together, these findings demonstrate that CYP51A1 transcription is controlled by a complex interplay of sterol-dependent, cAMP-responsive, and inhibitory pathways, raising important questions about how these signals are integrated in tissue-specific and disease contexts
Xue Y, Fleet JC
The research, published Thursday in JAMA Ophthalmology, found that after one year, more than twice as many people on GLP-1 drugs developed neovascular age-related macular degeneration compared to similar people who were not taking the drugs
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