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In mice, GLP-1 agonists reduced atherosclerosis even when weight loss was matched, supporting the weight-loss-independent mechanism
Brand-name medications carry significant costs, and insurance coverage varies widely
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Acid control does not imply symptom relief
Slower Titration Often Makes Sense GI side effects like nausea, vomiting, and diarrhea are the most common reason patients reduce their dose or discontinue GLP-1 therapy
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