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Our studys emphasis on direct cardiac and hepatic mechanisms, independent of significant weight loss, strengthens the rationale for exploring lower doses of GLP-1RAs in these diverse cardiovascular conditions to potentially maximize benefits while minimizing metabolic side effects

GenoHope can provide one-stop CDMO service from R&D to commercial production, especially for advanced intermediates and new compounds with special high quality and cost saving requirements.

This lack of flexibility may make it harder for some to stick with their treatment

GLP-1 medications are usually prescribed for people with type 2 diabetes or those with a higher body weight where other methods have not been successful

Mol Cell Endocrinol (2015) 404:2636