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**Pernicious Anemia:** Management of pernicious anemia, a condition characterized by the inability to absorb vitamin B12 from the gastrointestinal tract

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Effects on telomere length and cellular health appear to persist for months after completing a cycle, which is why extended off-cycle periods work within the protocol design

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Mitophagy might be also regulated by acid sphingomyelinase (ASM), a ceramide metabolite enzyme