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Multiple clinical trials have shown that semaglutide is an effective medication for weight loss, with patients losing an average of 15-20% of their body weight over a 6-12 month period

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More relevant to the GLP-1 claims, a separate 8-week randomized controlled crossover trial published in the European Journal of Nutrition found that participants taking the polyphenolic extract experienced a 12% increase in GLP-1 after breakfast and a 22% increase after lunch compared to placebo