Nevertheless, GLP-1 presented a rather ephemeral circulatory half-life, lasting a mere 12 min, due to the rapid enzymatic degradation by dipeptidyl peptidase IV (DPP-4), which markedly limits its biological efficacy [3,4,5]
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Emerging research underscores its neuroprotective potential, attributed to mechanisms including anti-oxidative, anti-apoptotic, and anti-inflammatory actions, as well as its regulatory impact on neurogenesis and synaptic plasticity
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