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In obesity, excess adipose tissue can lead to: Elevated oestrogen levels from peripheral conversion Insulin resistance affecting ovarian function Increased androgens contributing to anovulation Disrupted hypothalamic-pituitary-ovarian axis signalling As weight decreases with Saxenda treatment, these metabolic disturbances may improve
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They're typically marketed as a stack the claim being that they work on complementary pathways and produce a bigger pulse of GH together than either does alone
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