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Available evidence consistently demonstrates that GLP-1 RAs effectively improve blood glucose regulation in patients receiving glucocorticoid therapy, with significant reductions in HbA1c observed following treatment (3537)

FDA Approves Ozempic (Semaglutide) as the Only GLP-1 Ra to Reduce the Risk of Worsening Kidney Disease and Cardiovascular Death in Adults with Type 2 Diabetes and Chronic Kidney Disease, Novo Nordisk, 2025

The off period allows receptor density to normalize

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N.BuchholtzK.CusiK.LinderM.OkanoueT.RatziuV.et al (2021)