Creatine and Lean Body Mass Gains One key finding : creatine supplementation combined with resistance training consistently leads to greater increases in lean body mass compared to training alone
More recently, researchers have highlighted its impact on hair follicle stimulation, scalp circulation, and anti-inflammatory protection, making it a powerful candidate for hair restoration therapies (Pickart, Journal of Biomaterials Science )
It also reduces the risk of cardiovascular death, heart attack and stroke in patients who have overweight or obesity
The resulting downregulation of TLR4/NF-B/NLRP3 signaling led to suppressed cytokine storms and enhanced organ protection in septic mice (Zhao et al., 2025)
Enns GM, Berry SA, Berry GT, Rhead WJ, Brusilow SW, Hamosh A