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It enhances neurotransmitter regulation, which can support optimal nerve function
10 Additional observational analyses in patients with T2DM also suggested increased rates of pancreatitis and pancreatic cancer in GLP-1 RA users compared with other antidiabetic therapies
doi: 10.1038/s12276-023-01028-7 44 MorrisGBerkMGaleckiPWalderKMaesM
Two studies investigated animal models of comorbid depression and epilepsy 159,161 : one showed that exendin-4 led to an increase in frequency of absence seizures as well as depressogenic and anxiogenic responses 159 , while the other saw a decrease of depression-like behavior for liraglutide irrespective of concurrent use of the antiepileptic levetiracetam 161
