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Individuals with higher initial muscle mass relative to fat mass may experience greater absolute lean tissue loss, while those with severe obesity and limited muscle mass face different risks

This normalization results in healing

Because no long-duration human studies exist, the consequences of months or years of repeated dosing on the immune system, hormonal axes, or fibrotic tissue remodeling are simply unknown

However, doctors may also prescribe it off-label for weight loss or other health conditions

Satellite Cell Activation and Muscle Regeneration Growth hormone secretagogues such as MK-677, CJC-1295, and Ipamorelin enhance the GH/IGF-1 axis, increasing satellite cell proliferation and promoting new muscle fiber repair