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The most common issues are nausea, constipation, or diarrhoea
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In patients with type 2 diabetes at high cardiovascular risk, semaglutide demonstrated significantly lower rates of cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke compared to placebo, establishing the noninferiority of semaglutide
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In the current review we discuss the occurrence of adverse events associated with semaglutide focusing on hypoglycemia, gastrointestinal side effects, pancreatic safety (pancreatitis and pancreatic cancer), thyroid cancer, gallbladder events, cardiovascular aspects, acute kidney injury, diabetic retinopathy (DRP) complications and injection-site and allergic reactions and where available, we highlight potential underlying mechanisms
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