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Ageing potentiates diet-induced glucose intolerance, -cell failure and tissue inflammation through TLR4

In UK practice, monitoring is primarily based on clinical response rather than routine blood tests, as post-treatment serum B12 measurements can be misleadingly high and may not reflect tissue levels

The "half-step" approach: Some researchers soften the 2mg to 4mg transition by doing one week at 3mg before moving to 4mg

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doi: 10.1002/j.1460-2075.1988.tb03257.x 219 MassaguJ