ma research semaglutide bimagrumab Lilly stops trial of muscle-sparing obesity drug Obesity is moving beyond – Microdosing Semaglutide (the skinny shot)

10.1038/mp.2016.68 83

Seiwerth S, Rucman R, Turkovic B, Sever M, Klicek R, Radic B, Drmic D, Stupnisek M, Misic M, Vuletic LB, Pavlov KH, Barisic I, Kokot A, Japjec M, Blagaic AB, Tvrdeic A, Rokotov DS, Vrcic H, Staresinic M, Sebecic B, Sikiric P

Compounded semaglutide in convenient oral dissolving tablets for appetite control and metabolic support

No link with suicide thoughts or behavior Importantly, the results showed that GLP-1RAs were not associated with a worsening of mental state, suicidal behaviour, new mental illness diagnoses, or increased psychiatric admissions

While GLP-1s offer undeniable benefits, long-term adherence remains a problem, access barriers persist, and the regulatory landscape around compounded versions is uncertain