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Diagnosing and managing these conditions necessitate a comprehensive assessment by an ophthalmologist, who may employ a combination of clinical examination, laboratory tests, and imaging studies to ascertain the underlying cause and inflammation severity

In studies examining blood GSH in AD, 7 studies used the Hachiniski Ischaemic Score (HIS 4) to differentiate those with AD from those with potential vascular causes [41, 46, 55, 58, 60, 61, 69], and 5 of those studies further used neuroimaging to support diagnosis [55, 58, 60, 61, 69] (Table 2)

(2015) trial documented peak glutathione body stores at 3-6 months, with oxidized glutathione (GSSG) ratios normalizing indicating the antioxidant system was no longer under deficit stress

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