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The medication was discontinued in 2008 for commercial reasons and is now available off-label only through licensed US compounding pharmacies with a prescription
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Looking ahead, centralized multimodal repositories that integrate transcriptomic, proteomic and imaging data across neurological diseases will be essential to standardize reactive astrocyte definitions and foster cross-laboratory collaboration, ultimately refining subtype classification and accelerating translation
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The Semaglutide Data (STEP Trials) In the landmark STEP-1 trial (evaluating semaglutide 2.4 mg once weekly), adult participants lost an average of 14.9% of their body weight over 68 weeks, compared to just 2.4% in the placebo group
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