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Future clinical trials should refine the investigation of the direct analgesic properties of GLP-1RAs in osteoarthritis, differentiating these from the benefits linked to weight reduction, to better evaluate their clinical utility in managing osteoarthritis-related pain
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A severe-GI gate is present (gastroparesis / blockage / IBD), but that doesnt cover pancreatitis specifically
These effects are typically mild and transient, often resolving as the body adjusts to the medication
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